Capsules Manufacturing Process
🔹 1. Raw Material Preparation
All active pharmaceutical ingredients (APIs) and excipients are carefully selected and tested for purity, potency, and compatibility. Each material is weighed accurately and logged as per GMP protocols.
🔹 2. Blending and Mixing
Ingredients are uniformly blended using high-efficiency mixers to ensure even distribution of the drug. This step is crucial for dose accuracy and consistent therapeutic effect.
🔹 3. Capsule Shell Inspection
Empty hard gelatin or HPMC capsules are inspected for defects such as cracks or deformation. Only approved shells are used to maintain product integrity.
🔹 4. Encapsulation
The blended powder or pellets are filled into capsules using automatic or semi-automatic capsule-filling machines. Talwar Pharma ensures precision in fill weight and minimal powder loss.
🔹 5. Capsule Polishing and Sorting
Filled capsules are polished using soft brushes or polishing machines to remove any powder residues. They are then sorted to eliminate defective or low-weight capsules.
🔹 6. In-Process Quality Checks
Throughout the manufacturing process, in-process checks such as weight variation, disintegration, and appearance are carried out to ensure compliance with quality standards.
🔹 7. Packing and Labeling
After passing final quality checks, capsules are packed into blister packs, bottles, or bulk containers under controlled conditions. Each batch is labeled with complete traceability details.
🔹 8. Final Quality Assurance
Before release, the batch undergoes rigorous QC tests including assay, dissolution, microbial limits, and stability studies. Only products meeting all criteria are released for distribution.